Company Profile
Public information reviewed
- Public sources
- 1 reviewed
- Published leadership records
- 16
- Last reviewed
- Sep 16, 2026
Agent View
Machine representations
Inspect the same governed public record as Markdown, structured data, or a retrieval endpoint.
Markdown
https://registry.alpha.ac/companies/upstream-bio-inc.mdUpstream Bio, Inc.
Alpha governed public record. Unknown, unavailable, and unpublished values are never inferred as zero.
Record
| Field | Value |
|---|---|
| Representation | alpha-profile-markdown-v3 |
| Protocol | Alpha Governance Facts Protocol 0.1 |
| Schema | alpha.governance.entity.public.v1 |
| Record version | public-1 |
| Canonical entity | alpha:company:48d41dd7-a948-47aa-bb24-2e857eff5000 |
| Entity type | Company |
| Canonical URL | https://registry.alpha.ac/companies/upstream-bio-inc |
| Publication | PUBLISHED |
| Verification | source_reported |
| Verification schema | alpha-verification-states-v1 |
| Ownership | unclaimed |
| Published claims | 19 |
| Claims under review | 1 |
| Evidence records | 3 |
| Conflicts | 0 |
| Conflicts in internal review | 0 |
| Observed | 2026-09-16T04:46:23.098801+00:00 |
| Last reviewed | 2026-09-16T04:46:23.098801+00:00 |
Identity
- Legal name: Upstream Bio, Inc.
- Display name: Upstream Bio, Inc.
Leadership
- Allison Ambrose: Director. Valid from: 2024-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:evidence:company:48d41dd7-a948-47aa-bb24-2e857eff5000:2.
- Daniella Beckman: Director. Valid from: 2024-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:evidence:company:48d41dd7-a948-47aa-bb24-2e857eff5000:2.
- Danielle Beckman: Director. Valid from: 2026-04-16. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:evidence:company:48d41dd7-a948-47aa-bb24-2e857eff5000:2.
- E. Rand Sutherland: Director. Valid from: 2024-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:evidence:company:48d41dd7-a948-47aa-bb24-2e857eff5000:2.
- E. Rand Sutherland, M.D.: Chief Executive Officer and Director. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:evidence:company:48d41dd7-a948-47aa-bb24-2e857eff5000:3.
- Erez Chimovits, M.B.A., M.Sc.: Director. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:evidence:company:48d41dd7-a948-47aa-bb24-2e857eff5000:3.
- H. Edward Fleming, Jr: Director. Valid from: 2023-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:evidence:company:48d41dd7-a948-47aa-bb24-2e857eff5000:2.
- H. Edward Fleming, Jr., M.D.: Director. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:evidence:company:48d41dd7-a948-47aa-bb24-2e857eff5000:3.
- Liam Ratcliffe, M.B.Ch.B., Ph.D., M.B.A.: Director. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:evidence:company:48d41dd7-a948-47aa-bb24-2e857eff5000:3.
- Marcella Kuhlman Ruddy, M.D., M.S.: Director. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:evidence:company:48d41dd7-a948-47aa-bb24-2e857eff5000:3.
- Ronald C. Renaud, Jr., M.B.A.: Director. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:evidence:company:48d41dd7-a948-47aa-bb24-2e857eff5000:3.
- Aaron Deykin, M.D.: Chief Medical Officer and Head of Research and Development. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:evidence:company:48d41dd7-a948-47aa-bb24-2e857eff5000:3.
- Adam Houghton, Ph.D., M.B.A.: Chief Business Officer. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:evidence:company:48d41dd7-a948-47aa-bb24-2e857eff5000:3.
- Allison Ambrose, J.D.: Sr. Vice President, General Counsel and Secretary. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:evidence:company:48d41dd7-a948-47aa-bb24-2e857eff5000:3.
- E. Rand Sutherland, M.D.: Chief Executive Officer. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:evidence:company:48d41dd7-a948-47aa-bb24-2e857eff5000:3.
- Michael Paul Gray, M.B.A.: Chief Financial and Operating Officer. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:evidence:company:48d41dd7-a948-47aa-bb24-2e857eff5000:3.
Roles
- PUBLISHED
Governance
- NOT_ASSERTED
Board committees
- PUBLISHED
Financials
- NOT_ASSERTED
Workforce
- NOT_ASSERTED
Market and index context
- PUBLISHED
Legal Name
- Upstream Bio, Inc.. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:evidence:company:48d41dd7-a948-47aa-bb24-2e857eff5000:1.
Headquarters
- US. Publication: UNDER_REVIEW. Verification: source_reported. Assertion: source_reported. Evidence: unlinked, under review.
Entity Status
- Public listing published. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:evidence:company:48d41dd7-a948-47aa-bb24-2e857eff5000:1.
Published Fact
- US. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:evidence:company:48d41dd7-a948-47aa-bb24-2e857eff5000:1.
Coverage states
| Field | Value |
|---|---|
| Identity | PUBLISHED |
| Business | PUBLISHED |
| Leadership | PUBLISHED |
| Board and committees | PUBLISHED |
| Governance | NOT_ASSERTED |
| Financials | NOT_ASSERTED |
| Workforce | NOT_ASSERTED |
| Ownership | NOT_ASSERTED |
| Ratings | NOT_PUBLISHED |
| Market and index context | PUBLISHED |
Public sources
- alpha:evidence:company:48d41dd7-a948-47aa-bb24-2e857eff5000:1: Alpha canonical company public projection.
- alpha:evidence:company:48d41dd7-a948-47aa-bb24-2e857eff5000:2: DEF 14A upb-20260416.htm.
- alpha:evidence:company:48d41dd7-a948-47aa-bb24-2e857eff5000:3: SEC DEF 14A 0001193125-26-158966.
Rights
| Field | Value |
|---|---|
| public_retrieval | allowed |
| agent_retrieval | allowed |
| redistribution | not_granted |
| model_training | not_granted |
| commercial_use | not_specified |
| relationship_pathfinding | not_granted |
| direct_contact | not_granted |
Limitations
- Absence of a leadership role, committee, or disclosure is not evidence that it does not exist.
- Only explicitly published canonical company identity and current confirmed public roles are included.
- Absence of a board, committee, executive, listing, or claim is not evidence that it does not exist.
- Public retrieval does not grant redistribution, model-training, direct-contact, or relationship-pathfinding rights.
- This Company Profile is an identity and evidence record, not an Alpha rating.
Alternate representations
- Canonical profile
- Public Markdown
- Public JSON
- JSON-LD
- MCP resource:
alpha://companies/upstream-bio-incat https://mcp.alpha.ac/mcp