Agent View

Machine representations

Inspect the same governed public record as Markdown, structured data, or a retrieval endpoint.

Canonical entity
alpha:person:isaac-manke-ph-d
Schema
alpha.governance.entity.public.v1
Last reviewed
2026-05-16T06:23:52.011+00:00
Verification
corroborated
Ownership
unclaimed

Markdown

https://registry.alpha.ac/people/isaac-manke-ph-d.md
Open Markdown

Isaac Manke, Ph.D.

Alpha governed public record. Unknown, unavailable, and unpublished values are never inferred as zero.

Record

FieldValue
Representationalpha-profile-markdown-v3
ProtocolAlpha Governance Facts Protocol 0.1
Schemaalpha.governance.entity.public.v1
Record versionpublic-0
Canonical entityalpha:person:isaac-manke-ph-d
Entity typePerson
Canonical URLhttps://registry.alpha.ac/people/isaac-manke-ph-d
PublicationPUBLISHED
Verificationcorroborated
Verification schemaalpha-verification-states-v1
Ownershipunclaimed
Published claims11
Claims under review0
Evidence records5
Conflicts0
Conflicts in internal review1
Observed2026-09-13T09:26:36.672562+00:00
Last reviewed2026-05-16T06:23:52.011+00:00

Identity

  • Legal name: Isaac Manke, Ph.D.
  • Display name: Isaac Manke, Ph.D.

Leadership

  • PUBLISHED

Roles

  • Director at OnKure Therapeutics, Inc.. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:evidence:person:isaac-manke-ph-d:2.
  • Director at Q32 Bio Inc.. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:evidence:person:isaac-manke-ph-d:5.

Governance

  • PUBLISHED

Board committees

  • PUBLISHED

AI and ML experience

  • AI and ML experience: not identified in the cited filing. Publication: PUBLISHED. Verification: corroborated. Assertion: source_reported. Evidence: alpha:evidence:person:isaac-manke-ph-d:4, alpha:evidence:person:isaac-manke-ph-d:3.

Board role

  • Board role: Director. Publication: PUBLISHED. Verification: corroborated. Assertion: source_reported. Evidence: alpha:evidence:person:isaac-manke-ph-d:1, alpha:evidence:person:isaac-manke-ph-d:4.

Committee assignments

  • No committee assignment disclosed in the cited filing. Publication: PUBLISHED. Verification: corroborated. Assertion: source_reported. Evidence: alpha:evidence:person:isaac-manke-ph-d:1, alpha:evidence:person:isaac-manke-ph-d:4.

Cybersecurity experience

  • Cybersecurity experience: not identified in the cited filing. Publication: PUBLISHED. Verification: corroborated. Assertion: source_reported. Evidence: alpha:evidence:person:isaac-manke-ph-d:4, alpha:evidence:person:isaac-manke-ph-d:3.

Executive company

  • Executive at Acorn Bioventures. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:evidence:person:isaac-manke-ph-d:4.
  • Executive at OnKure Therapeutics, Inc.. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:evidence:person:isaac-manke-ph-d:3.

Executive title

  • Executive title: Senior Vice President, Business Development. Publication: PUBLISHED. Verification: corroborated. Assertion: source_reported. Evidence: alpha:evidence:person:isaac-manke-ph-d:1, alpha:evidence:person:isaac-manke-ph-d:3.

Technology background

  • Technology background: not identified in the cited filing. Publication: PUBLISHED. Verification: source_reported. Review: internal_review. Assertion: source_reported. Evidence: alpha:evidence:person:isaac-manke-ph-d:4.
  • Technology background reported in filings. Publication: PUBLISHED. Verification: source_reported. Review: internal_review. Assertion: source_reported. Evidence: alpha:evidence:person:isaac-manke-ph-d:3.

Coverage states

FieldValue
IdentityPUBLISHED
BusinessNOT_APPLICABLE
LeadershipPUBLISHED
Board and committeesPUBLISHED
GovernancePUBLISHED
FinancialsNOT_APPLICABLE
WorkforceNOT_APPLICABLE
OwnershipNOT_APPLICABLE
RatingsNOT_PUBLISHED
Market and index contextNOT_APPLICABLE

Public sources

Rights

FieldValue
public_retrievalallowed
agent_retrievalallowed
redistributionnot_granted
model_trainingnot_granted
commercial_usenot_specified
relationship_pathfindingnot_granted
direct_contactnot_granted

Limitations

  • Only permissioned public claims and evidence are included.
  • Absence of a claim is not evidence that the underlying fact is false.
  • Public retrieval does not grant model-training or redistribution rights.
  • Private relationships and Council activity are excluded.

Alternate representations